What is Acetylcholine?

Acetylcholine is a neurotransmitter that plays a crucial role in the brain. It is involved in the excitation of the parasympathetic nervous system, inhibition of the sympathetic nervous system, and transmission of motor nerve signals. Additionally, acetylcholine is deeply connected to cognitive functions such as thinking, memory, learning, attention, and concentration, as well as wakefulness and sleep (especially REM sleep). By stimulating the hippocampus and promoting the generation of theta waves, acetylcholine facilitates synaptic connections, enhancing memory retention and creativity. It also influences emotional memory.

The Effectiveness of Acetylcholine

Acetylcholine contributes to efficient work and improved creativity. For instance, controlling acetylcholine levels is known to enhance efficient work and creativity. Furthermore, increased secretion of acetylcholine during sleep promotes rest for the brain and body.

Effects of Acetylcholine Deficiency

A deficiency in acetylcholine can lead to cognitive decline and memory impairment. In particular, Alzheimer’s disease is characterized by a reduction in neurons that produce acetylcholine, leading to progressive cognitive decline.

Lifestyle Habits to Increase Acetylcholine

To increase acetylcholine levels, the following lifestyle habits are effective:

• Quit Smoking: Nicotine binds to receptors in place of acetylcholine, inhibiting its production. Therefore, quitting smoking is recommended.
• Consume Lecithin: Lecithin, found in egg yolks, soybeans, grains, liver, and nuts, helps in the production of acetylcholine.
• Take Short Naps: Napping for less than 30 minutes can reduce the risk of Alzheimer’s disease and improve performance. However, naps longer than 60 minutes may have the opposite effect.
• Be Cautious with Cold Medications: Cold medications with anticholinergic effects, such as diphenhydramine and scopolamine, can inhibit acetylcholine and reduce cognitive function and concentration.
• Take Action: The nucleus accumbens contains acetylcholine, and initiating an action stimulates this area, leading to the secretion of acetylcholine. This enhances work efficiency and makes it easier to continue tasks.

References

• Dementia Care Information Network. “Medications to Increase Acetylcholine.”
• Japan Agency for Medical Research and Development. “Signal Transduction of Acetylcholine in Neurons Controlling Learning and Memory.”
• Omron Healthcare. “Foods to Keep the Brain Healthy and Prevent Stroke and Dementia.”
• Osaka University. “Shedding Light on the Mechanisms of Memory Impairment in Alzheimer’s Disease and Other Dementias.”
• Tokyo Metropolitan Institute of Gerontology. “Why Walking Helps Prevent Dementia.”